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This volume illustrates the process of conducting interdisciplinary, multi-cultural research into the relationship between patient language use and chronic disease management. The ten chapters in this book provide a model for interdisciplinary research in health discourse from start to finish. Part I describes in detail the conceptualization and design of a multi-year research project exploring language use among people living with diabetes. Part II offers a sampler of a variety of qualitative, quantitative, and contrastive methodologies that have considerable potential in the study of health discourse. Part III brings the research process full circle by discussing issues related to adapting research protocols to diverse cultural contexts, translating results into practice, and working in interdisciplinary teams.