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Papers in this volume highlight the increasing role of the Internet and digitization in the changing nature of innovation, entrepreneurship, and innovation policy. The first offers an overview of the impact of "big data" on the ability to conduct novel types of measurement and research in economics and related fields. The second highlights research designs used to evaluate the interplay between piracy, the availability of legitimate digital channels, and the impact of anti-piracy enforcement efforts. The third provides an overview of the rapidly emerging area of crowd funding, while the fourth focuses on the role of standard-setting organizations. The volume concludes with a look at geographic clusters, entrepreneurship, and innovation.