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Through close analysis of texts, cultural and civic communities, and intellectual history, the papers in this collection, for the first time, propose a dynamic relationship between rhetoric and medicine as discourses and disciplines of cure in early modern Europe. Although the range of theoretical approaches and methodologies represented here is diverse, the essays collectively explore the theories and practices, innovations and interventions, that underwrite the shared concerns of medicine, moral philosophy, and rhetoric: care and consolation, reading, policy, and rectitude, signinference, selfhood, and autonomy-all developed and refined at the intersection of areas of inquiry usually thought distinct. From Italy to England, from the sixteenth through to the mid-eighteenth century, early modern moral philosophers and essayists, rhetoricians and physicians investigated the passions and persuasion, vulnerability and volubility, theoretical intervention and practical therapy in the dramas, narratives, and disciplines of public and private cure. The essays are relevant to a wide range of readers, including cultural, literary, and intellectual historians, historians of medicine and philosophy, and scholars of rhetoric.