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The effects of spatial location on socio-economic development is a critical issue in urban and regional planning. This comprehensive work examines the success or failure of an urban place in relation to the spatial characteristics of the urban cluster to which it belongs. Employing case studies from a variety of countries, it analyzes relationships between the clustering of towns and their attractiveness to migrants and investors. In addition it provides a fundamental overview and critical analysis of basic concepts in the field of urban and regional location, introducing new methods for assessing the sustainability of urban growth in central and peripheral regions. The book also proposes planning strategies designed to enhance the potential of urban growth.